Found 362 matching trials
A Study to Evaluate the Safety of Concurrent Durvalumab With CRT Followed by Durvalumab for Chinese Unresectable Stage III NSCLC PHASE2 This is a prospective, multi-center, single arm study assessing the efficac...
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Henan Cancer Hospital
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Safety Study of MKC-1 Combined With Pemetrexed to Treat Advanced Cancer and Non-Small Cell Lung Cancer PHASE1 To determine the toxicities, maximum tolerated dose (MTD) and recommended p...
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Indiana University Cancer Center
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A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer PHASE3 The purpose of this study is to evaluate the efficacy and safety of divaras...
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Alaska Oncology and Hematology
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A Safety and Tolerability Study of NC318 in Combination With Chemotherapy for Subjects With Advanced or Metastatic NSCLC PHASE1 This research study is studying an investigational drug, NC318, as a possib...
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Multiple Locations
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Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression PHASE2 Background:
Major depressive disorder (MDD) is a serious mental illness th...
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National Institutes of Health Clinical Center
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Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC PHASE3 This randomized, Phase III, multicenter, open-label study designed to evalu...
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Samsung Medical Center
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Aumolertinib With Chemotherapy or Alone Compared With Osimertinib in Patients With Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer PHASE3 Aumolertinib is a third-generation epidermal growth factor receptor (EGFR) ...
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Highlands Oncology Group
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Study of Pembrolizumab (MK-3475) Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (MK-3475-024/KEYNOTE-024) PHASE3 This is a study to assess the efficacy and safety of pembrolizumab (MK-3475...
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Multiple Locations
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Erlotinib Versus Pemetrexed as Second-Line Therapy in Treating Patients With Advanced Lung Adenocarcinoma PHASE2 Both pemetrexed and erlotinib are second-line treatment options for patient...
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Sun Yat-sen University Cancer Center
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Pemetrexed +/- Carboplatin as Second Line Treatment in NSCLC PHASE2 The aim of this study is to compare time to progression between the combina...
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Azienda Ospedaliero-Universitaria Umberto I, Clinica di Oncologia Medica
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